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Kaylee Ermine



B.S. Chemical Engineering, The Pennsylvania State University
Headshot of Kaylee Ermine

Journal Articles

Tong J, Tan X, Hao S, Ermine K, Lu X, Liu Z, Jha A, Yu J, Zhang L. Inhibition of multiple CDKs potentiates colon cancer chemotherapy via p73-mediated DR5 induction. Oncogene. 2023 Mar;42(12):869-880. doi: 10.1038/s41388-023-02598-6. Epub 2023 Jan 31. PMID: 36721000
Kuang C, Tong J, Ermine K, Cai M, Dai F, Hao S, Giles F, Huang Y, Yu J, Zhang L. Dual inhibition of BET and HAT/p300 suppresses colorectal cancer via DR5- and p53/PUMA-mediated cell death. Front Oncol. 2022 Oct 12;12:1018775. doi: 10.3389/fonc.2022.1018775. eCollection 2022. PMID: 36313707
Tong J, Tan X, Song X, Gao M, Risnik D, Hao S, Ermine K, Wang P, Li H, Huang Y, Yu J, Zhang L. CDK4/6 Inhibition Suppresses p73 Phosphorylation and Activates DR5 to Potentiate Chemotherapy and Immune Checkpoint Blockade. Cancer Res. 2022 Apr 1;82(7):1340-1352. doi: 10.1158/0008-5472.CAN-21-3062. PMID: 35149588; PMCID: PMC8983601.
Tong J, Tan X, Risnik D, Gao M, Song X, Ermine K, Shen L, Wang S, Yu J, Zhang L. BET protein degradation triggers DR5-mediated immunogenic cell death to suppress colorectal cancer and potentiate immune checkpoint blockade. Oncogene. 2021 Dec;40(48):6566-6578. doi: 10.1038/s41388-021-02041-8. Epub 2021 Oct 6. PMID: 34615996; PMCID: PMC8642302.
Ermine K, Yu J, Zhang L. Role of Receptor Interacting Protein (RIP) kinases in cancer. Genes Dis. 2021 Nov 18;9(6):1579-1593. doi: 10.1016/j.gendis.2021.10.007. PMID: 36157481; PMCID: PMC9485196.

Awards and Honors

John S. Lazo Cancer Pharmacology Fellowship- September 1, 2020-August31, 2021
Molecular Pharmacology Predoctoral Training in Pharmacological Sciences, T32 GM133332 September 1, 2021 to August 31, 2022