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Pharmacology & Chemical Biology Seminar Series
2/23/2023 - 12:00 PM-1:00 PM
"May the Force Be with You: Vascular Piezo1 and the Cerebral Blood Flow Symphony" (tentative)

Osama Harraz, PhD 
Assistant Professor
Department of Pharmacology
Larner College of Medicine
University of Vermont

Changes in blood flow to match brain activity are essential for brain health, but the consequences of accompanying mechanical forces are not fully understood. We recently discovered that the central nervous system blood vessels sense forces through the actions of the Piezo1 channel. In my talk, I will share recent evidence from our group that Piezo1 is crucial in regulating cerebral blood flow, and how this role is impaired during cardiovascular disease. 

Thomas E. Starzl Biomedical Science Tower
1395 Conference Room
203 Lothrop St
Pittsburgh, PA 15213
Melanie Hoffner

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