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Home
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Secondary Faculty
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Julie Eiseman, PhD
Julie Eiseman, PhD
Professor
Education
BS (Chemistry), University of Michigan, Ann Arbor, MI, 1969
MS (Pharmacology), Michigan State University, East Lansing, MI, 1971
PhD (Pharmacology), Cornell University Medical College, New York, NY, 1980
Links
PubMed
NIH RePORTer
Research Details
Publications
Labs
Eiseman Lab
Research Areas
Cancer Pharmacology
Protein Kinases & Phosphatases
Journal Articles
Eiseman J
, J Lan, J Guo, E Joseph and Vucenik I. Pharmacokinetics and tissue distribution of inositol hexaphosphate in C.B17 SCID mice bearing human breast cancer xenografts. Metabolism 60:1465-1474, 2011.
Beumer JH,
JL Eiseman
, J Gilbert, JL Holleran, A Yellow-Duke, D Clausen, D D'Argenio, M Ames P Hershberger, RA Parise, L Bai, JA Covey and ML Egorin. Plasma pharmacokinetics and oral bioavailabiity of the 3,4,5,6-tetrahydrouridine (THU) prodrug, triacetyl-THU (taTHU) in mice. Cancer Chemother Pharmacol 67:421-430, 2011.
Zamboni WC,
Eiseman JL
, S Strychor, PM Rice, E Joseph, BA Zamboni, MK Donnelly, J Shurer, RA Parise, ME Tonda, NY Yu and PH Basse. Tumor disposition of pegylated liposomal CKD-602 and the reticuloendothelial system in preclinical tumor models. J Liposome Res 21:70-80, 2011.
Holleran JL, RA Parise, AE Yellow-Duke, MJ Egorin,
JL Eiseman
, JM Covey and JH Beumer. Liquid chromatography-tandem mass spectrometric assay for the quantitation in human plasma of the novel indenoisoquinoline topoisomerase I inhibitors, NSC 743400 and NSC 725776. J Pharm Biomed Anal 52:714-720, 2010.
Clausen DM, J Guo, RA Parise, JH Beumer, MJ Egorin, JS Lazo, EV Prochownik and
JL Eiseman
.
In vitro
cytotoxicity and
in vivo
efficacy, pharmacokinetics and metabolism of 10074-G5: A novel small-molecule inhibitor of C-Myc/Max dimerization. J Pharmacol Exp Ther 335:715-727, 2010.
Guo P, RA Parise, E Joseph, MJ Egorin, EK Prochownik and
JL Eiseman
. Efficacy, pharmacokinetics, tissue distribution, and metabolism of the Myc-Max disruptor, 10058-F4 [Z,E]-[4-ethylbenzylidine]-2-thioxothiazolidin-4-one, in mice. Cancer Chemother Pharmacol 63:615-625, 2009.
Bai L, J Guo, FA Bontempo and
JL Eiseman
. The relationship of phthalocyanine 4 (Pc 4) concentrations measured non-invasively to outcome of Pc 4 photodynamic therapy in mice. Photochemistry and Photobiology 85:1011-1019, 2009.
Beumer JH,
JL Eiseman
, RA Parise, JM Covey and MJ Egorin. Modulation of gemcitabine (2',2'-difluoro-2'-deoxycytidine) pharmacokinetics, metabolism, and bioavailability in mice by 3,4,5,6-tetrahydrouridine. Clin Cancer Res 14:3529-3535, 2008.
Eiseman JL
, L Bai, W-H Jung, J Moura-Letts, BW Day and DP Curran. Improved synthesis of 6-epi-dictyostatin and antitumor efficacy in mice bearing MDA-MB231 human breast cancer xenografts. J Med Chem 51:6650-6653, 2008.