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“The secret life of G proteins”
Pharmacology & Chemical Biology Seminar Series
12/15/2022 - 12:00 PM-1:00 PM
“The secret life of G proteins”
Mikel Garcia-Marcos, PhD
Professor
Department of Biochemistry
Boston University School of Medicine
Our research program aims to understand the mechanisms and consequences cell communication via heterotrimeric G-proteins (Gαβγ) because they represent major intracellular hubs of signaling with very direct biomedical relevance. To achieve this goal, we use a wide range of approaches (biochemistry, cell biology, genetics, drug screening/ development) and experimental systems (purified proteins, cultured cells, model organisms) in combination with the development of novel tools (biosensors, chemogenetics, optogenetics). Our ongoing efforts have direct implications in cancer, embryonic development defects, and neurological disorders.
Thomas E. Starzl Biomedical Science Tower
1395 Conference Room
203 Lothrop St
Pittsburgh, PA 15213
Contact
Melanie Hoffner